MOTS-c Reconstitution Calculator: BAC Water, mL and Units

Pick your MOTS-c vial size and enter how much water you add to see the concentration and how much is in each unit on a U-100 syringe. Enter an amount and it also gives the units to draw. Quick picks are shortcuts for vial sizes; always use the amount printed on your own vial.

MOTS-c reconstitution table

What different amounts of water give you, for each quick-pick vial size. This is arithmetic, not a recommendation: the right amount of water is whatever makes your measurements easy and matches any instructions you were given.

MOTS-c concentration by vial size and water added, on a U-100 syringe
Vial	Water	Concentration	Per unit (0.01 mL)	Per 10 units (0.1 mL)
5 mg	1 mL	5 mg/mL	50 mcg	500 mcg
5 mg	2 mL	2.5 mg/mL	25 mcg	250 mcg
5 mg	3 mL	1.67 mg/mL	16.67 mcg	167 mcg
10 mg	1 mL	10 mg/mL	100 mcg	1 mg
10 mg	2 mL	5 mg/mL	50 mcg	500 mcg
10 mg	3 mL	3.33 mg/mL	33.33 mcg	333 mcg

How the math works for MOTS-c

A 10 mg MOTS-c vial holds 10,000 mcg. Mixed with 2 mL of water, that's 10,000 ÷ 2 = 5,000 mcg per mL. One unit on a U-100 syringe is 0.01 mL, so each unit holds 50 mcg. More water spreads the same 10 mg across more units; less water packs it into fewer.

Concentration (mcg per mL) = vial (mg) × 1,000 ÷ water (mL)
mcg per unit = concentration ÷ 100
Units to draw = amount (mcg) ÷ mcg per unit

A peptide vial label with the vial size circled. The mg number is the total amount in the vial, and 1 mg equals 1,000 mcg — Use the mg number printed on your own MOTS-c vial, not the quick-pick size, if they differ.

What is MOTS-c?

MOTS-c is a 16-amino-acid peptide encoded in mitochondrial DNA, first described by researchers in 2015. That original study, done in mice, linked it to insulin sensitivity and metabolism.

Frequently asked questions

How much water do I add to a 10 mg MOTS-c vial?

There's no single right amount. Less water makes each unit stronger and harder to measure; more water makes each unit weaker and easier to measure. For a 10 mg vial, 1 mL gives 100 mcg per unit, 2 mL gives 50 mcg, and 3 mL gives 33.33 mcg. If your MOTS-c was prescribed, use the amount in your prescription instructions.

How many mcg of MOTS-c are in one unit?

It depends on the vial size and how much water you add: mcg per unit = (mg in the vial × 1,000) ÷ (mL of water × 100). With a 10 mg vial and 2 mL of water, that's 50 mcg per unit on a U-100 syringe.

Is MOTS-c FDA approved?

No. MOTS-c isn't an FDA-approved drug. Removed from Category 2 in April 2026. Recommended for the 503A bulks list on July 23, 2026, against FDA staff's recommendation.

Other peptide calculators

General reconstitution calculator · Peptide FDA status tracker